TCT 2026: CT-guided PCI Matches IVUS Outcomes in Randomized P4 Trial; Heartflow PCI Navigator Changes PCI Plans in Approximately 70% of Patients

Heartflow announced landmark clinical data from the P4 randomized trial showing CT-guided PCI planning matches gold-standard IVUS outcomes for one-year clinical results while reducing procedure time by 27% and contrast volume by 12%. The NAVIGATE-PCI registry demonstrated that Heartflow PCI Navigator modified treatment plans in approximately 70% of patients, primarily affecting stent length and lesion preparation decisions.