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Shattuck Labs Announces Phase 1 Results for SL-325

GlobeNewswire Inc.·
Shattuck Labs Announces Phase 1 Results for SL-325

Shattuck Labs announced encouraging Phase 1 clinical trial results for SL-325, its lead DR3 blocking antibody candidate, showing a potentially best-in-mechanism immunogenicity profile with only 3.7% of participants developing antidrug antibodies, complete DR3 blockade at low doses, and a favorable safety profile. The company plans to initiate the RECEPTIVE-CD1 Phase 2b trial in Crohn's disease patients in Q3 2026, with lead bispecific candidate SL-846 expected to enter Phase 1 in H1 2027.

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