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Immatics Presents Clinical Activity of IMA402 PRAME Bispecific and IMA203CD8 PRAME Cell Therapy across Advanced Solid Tumors in Two Oral Presentations at 2026 ESMO Annual Meeting

GlobeNewswire Inc.·
Immatics Presents Clinical Activity of IMA402 PRAME Bispecific and IMA203CD8 PRAME Cell Therapy across Advanced Solid Tumors in Two Oral Presentations at 2026 ESMO Annual Meeting

Immatics announced updated clinical trial data for its PRAME-targeting therapies at the 2026 ESMO Annual Meeting. IMA402 bispecific achieved a 32% confirmed objective response rate in PRAME-high melanoma patients with a 12.5-month median duration of response and 91% one-year overall survival rate. IMA203CD8 cell therapy demonstrated a 55% response rate in gynecologic cancers at clinically relevant doses with an 8.4-month median duration of response. Both therapies showed favorable safety profiles, supporting continued development across multiple solid tumor indications.

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