Down 45% Or More This Year, Are Any of These Once-Popular Altcoins Worth Buying?

Major Layer-1 blockchain networks have declined 45-55% in 2026, presenting potential buying opportunities. Ethereum and Solana are positioned as the strongest contenders with analyst price targets suggesting significant upside, while weaker competitors like Cardano and Avalanche should be avoided. Niche Layer-1 blockchains like Bittensor (AI-focused) and Stable (stablecoin-focused) have outperformed the broader market.